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toluene degradation to 2-hydroxypentadienoate (via toluene-cis-diol)

State Icon Reaction EC-Number Confidence maximal confidence score from EnzymeDetector
3-methylcatechol + O2 <=> 2-hydroxy-6-oxohepta-2,4-dienoate + H+ 1.13.11
1.13.11.16 3-carboxyethylcatechol 2,3-dioxygenase
1.13.11.2 catechol 2,3-dioxygenase
1.13.11.39 biphenyl-2,3-diol 1,2-dioxygenase
1.13.11.56 1,2-dihydroxynaphthalene dioxygenase





NAD+ + (1S,2R)-3-Methylcyclohexa-3,5-diene-1,2-diol <=> H+ + NADH + 3-methylcatechol 1.3.1.19 cis-1,2-dihydrobenzene-1,2-diol dehydrogenase

2-hydroxy-6-oxohepta-2,4-dienoate + H2O <=> (2Z)-2-hydroxypenta-2,4-dienoate + H+ + acetate 3.7.1.25 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase

Toluene + O2 + NADH + H+ <=> (1S,2R)-3-Methylcyclohexa-3,5-diene-1,2-diol + NAD+ 1.14.12.11 toluene dioxygenase

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